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KMID : 1007520230320020135
Food Science and Biotechnology
2023 Volume.32 No. 2 p.135 ~ p.144
Effect of gelation technique on lipid digestibility of emulsion-loaded alginate microparticles: a systematic review and meta-analysis
Lei Cao

Jeong Seung-Jin
Shin Joong-Ho
Abstract
Alginate microparticles fabricated via calcium gelation or layer-by-layer assembly are commonly used for encapsulating emulsions. In this study, the impact of these two gelation methods on the lipid digestibility of emulsions was reviewed through a systematic screening of relevant studies. From the literature search (Scopus, PubMed, and Web of Science databases), 604 records were screened and 25 articles were included in the analysis. The fold change of free fatty acid release rate at the end of in vitro digestion process between alginate-encapsulated emulsion and emulsions not encapsulated by alginate was calculated for calcium gelation (weighted mean of response ratio 0.64, 95% CI 0.54?0.75) and layer-by-layer assembly (weighted mean of response ratio 0.89, 95% CI 0.81?0.98). Alginate?calcium hydrogels showed stronger inhibition of the extent of lipid digestion than alginate-coated multilayer emulsions. The structural and particle size differences between alginate microparticles acquired using different techniques may contribute to this phenomenon.
KEYWORD
Lipid digestibility, Alginate, Gelation, Calcium, Layer-by-layer
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